I work as an assistant professor in the Computational Biology Department at Adam Mickiewicz University in Poznan (Poland).
I'm interested in developing computational methods for identification of homologous protein domains that are composed of divergent sequences and still perform equate molecular function in cell. These domains show extremely low sequence similarity and this escape recognition by standard alignment-based algorithms (e.g., BLAST, HMMER).
- alignment-free sequence comparison
- annotation of protein domains
- identification of orthologous genes
- web applications & databases